Presentations

Mihaila, I., Hartley, S. L., Handen, B. L., Hardison, R., Devenny, D., Lao, P. J., Klunk, W. E., & Christian, B. T. (2017, March). Declines in Cognitive Functioning Related to Increasing Amyloid-β over 3-years in Adults with Down syndrome. Paper resented at the Gatlinburg Conference on Theory and Research in Intellectual and Developmental Disabilities. San Antonio, TX.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Tudorasco D, Devenny DA, Johnson SC, Handen BL, Christian BT. Alzheimer-like pathophysiological changes in the non-demented Down syndrome population. Oral presentation. 29th Alzheimer’s Association International Conference, 2017, London, England.

Cohen AD, Laymon CM, Minhas D, Wolfe C, Lao P, Mathis C, Sabbagh M, Zaman S, Klunk W, Handen B, Christian B. [F-18]AV-1451 PET in non-demented adults with Down Syndrome is related to both amyloid and cognition. Poster presentation. 29th Alzheimer’s Association International Conference, 2017, London, England.

Lao P, Handen B, Betthauser T, Price J, Klunk W, Bulova P, Hartley S, Hardison R, Tumuluru R, Murali D, Mathis C, Cohen A, Barnhart T, Tudorascu D, Devenny D, Johnson S, Christian B. Amyloid accumulation, glucose hypometabolism, and gray matter atrophy in adults with Down syndrome. Oral Presentation. 64th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, 2017, Denver, Colorado.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Tudorasco D, Devenny DA, Johnson SC, Handen BL, Christian BT. Amyloid-β plaque accumulation and glucose hypometabolism in non-demented adults with Down syndrome demonstrate pattern of association observed in Alzheimer’s disease. Oral Presentation. 13th Conference on Quantification of Brain Function with PET, 2017, Berlin, Germany.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Tudorasco D, Devenny DA, Johnson SC, Handen BL, Christian BT. Association of amyloid-β plaque accumulation and glucose hypometabolism in Down syndrome demonstrates pattern associated with Alzheimer’s disease. Oral presentation. 11th Annual Human Amyloid Imaging Conference, 2017, Miami, FL.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Tudorasco D, Devenny DA, Johnson SC, Handen BL, Christian BT. Considerations for defining a striatal region of interest in amyloid PET studies within the Down syndrome population. Poster presentation. 11th Annual Human Amyloid Imaging Conference, 2017, Miami, FL.

Betthauser TJ, Lao PJ, Tudorascu DL, Price JC, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Minhas D, Laymon CM, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Klunk WE, Johnson SC, Handen BL, Christian BT. Comparison of region of interest segmentation methods for extraction of 11C-PiB SUVR in the Down syndrome population. Poster presentation. 11th Annual Human Amyloid Imaging Conference, 2017, Miami, FL.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Lopresti BJ, Haridison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Tudorascu D, Devenny DA, Johnson SC, Handen BL, Christian BT. Longitudinal PET study of amyloid-β accumulation rates in Down syndrome. The 11th International Symposium on Functional NeuroReceptor Mapping of the Living Brain, Boston, MA, July 13-16, 2016.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Lopresti BJ, Haridison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Johnson SC, Handen BL, Christian BT. Longitudinal study of amyloid-β accumulation in Down syndrome. Society of Nuclear Medicine and Molecular Imaging Annual Meeting. San Diego, CA, June 11-15, 2016.

Lao PJ, Betthauser TJ, Price JC, Klunk WE, Bulova PD, Hartley SL, Haridison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Johnson SC, Handen BL, Christian BT. [C-11]PiB imaging in the Down syndrome population: A closer investigation of amyloid burden in the striatum. 10th Human Amyloid Imaging Conference, Miami, FL, Jan. 13-15, 2016.

Lao PJ, Betthauser TJ, Hillmer AT, Price JC, Klunk WE, Mihaila I, Higgins AT, Bulova PD, Hartley SL, Hardison R, Tumuluru D, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Mailick MR, Johnson SC, Handen BL, Christian BT. [11C]PiB imaging in a nondemented Down syndrome population to determine the natural relationship between amyloid-B deposition and aging. Society of Nuclear Medicine and Molecular Imaging 2015, Baltimore, MD June 6 – 10, 2015.

McDade E, Cohen A, Christian BT, Price J, Mathis C, Klunk W, Handen B. Early striatal binding of PiB-PET amyloid distinguishes Down’s syndrome and autosomal dominant Alzheimer dementia mutation carriers from late onset deposition. 9th Human Amyloid Imaging, Miami, FL January 14-16, 2015.

Lao PJ, Betthauser TJ, Hillmer AT, Price JC, Klunk WE, Mihaila I, Higgins AT, Bulova PD, Hartley SL, Hardison R, Tumuluru D, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Mailick MR, Johnson SC, Handen BL, Christian BT. Imaging age-related effects on amyloid-β deposition in nondemented adults with Down syndrome using [11C]PiB. 9th Human Amyloid Imaging, Miami, FL January 14-16, 2015.

Lao PJ, Betthauser TJ, Hillmer AT, Tudorascu DL, Price JC, Klunk WE, Mihaila I, Higgins AT, Bulova PD, Hartley SL, Hardison R, Tumuluru D, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Mailick MR, Johnson SC, Handen BL, Christian BT. Gray matter volume associations with amyloid-B deposition and age in Down syndrome. XIIth International Conference on Quantification of Brain Function with PET, Vancouver, Canada, June 27-30, 2015.

Handen BL, Cohen AD, MaDade E, Christian BT, Hardison R, Price JC, Klunk WE. Comparison of Beta-Amyloid Distribution Patterns in Healthy Adults with Down Syndrome, Non-Demented Elderly Controls and Presenilin-1 Carriers. Alzheimer’s Disease in Down Syndrome: From molecules to cognition, Cambridge, UK, March 27-29, 2014.

Christian BT, Barnhart TE, Bulova PD, Devenny D, Hardison RM, Hillmer AT, Johnson SC, Klunk WE, Mathis CA, Murali D, Price JC, Seltzer MM, Wooten DW, Handen BL. Increasing Amyloid Burden with Age in Individuals with Down Syndrome. 7th Human Amyloid Imaging, Miami, FL, Jan. 16-18, 2013.

Hartley SL, Handen B, Christian BT, Murray PJ, Price J, Johnson S, Klunk W, Devenny D. Preclinical stage of Alzheimer’s disease: The neuropsychological profile of asymptomatic adults with Down syndrome evidencing amyloid deposition. Gatlinburg Conference on Research and Theory in Intellectual and Developmental Disabilities. Annapolis, MD, March 7-9, 2012.

Price JC, Christian BT, Klunk WE, Cohen AD, Hartley SL, Seltzer MM, Johnson SC, Murali D, Bulova PD, Tumuluru R, Lopresti BL, Mathis CA, Handen BL. Assessing Amyloid Load in Non-demented Young Adults with Down's Syndrome. American College of Neuropsychopharmacology, Hawaii, 2011.

Cohen AD, Christian BT, Handen B, Johnson S, Hartley S, Seltzer M, Murali D, Bergnic M, Matan C, Price JC, Mathis CA, Klunk WE. Imaging brain amyloid in non-demented young adults with Down syndrome using PiB-PET. International Conference on Alzheimers Disease. Paris, France, 2011.